May 2022 Content Release Copied

05/26/20222022 ContentContent releasePhysician, Clinical, Admin, Billing

Clinical Profile Documentation

Additions

The Clinical Profile ‘Problems’ sub-tab now includes Line of Therapy to accommodate documentation points for Dermatofibrosarcoma protuberans (disorder).

Problems

The following items are available for documentation in Problems and appear on the Charge Capture Report (CCR). Additional ICD-10 codes* may display to present the surrounding nodes.

Problem	ICD-10 Codes*
Abdominal pain (finding)	R10.0 Acute abdomen R10.10 Upper abdominal pain, unspecified R10.11 Right upper quadrant pain R10.12 Left upper quadrant pain R10.13 Epigastric pain R10.2 Pelvic and perineal pain R10.30 Lower abdominal pain, unspecified R10.31 Right lower quadrant pain R10.32 Left lower quadrant pain R10.33 Periumbilical pain R10.811 Right upper quadrant abdominal tenderness R10.812 Left upper quadrant abdominal tenderness R10.813 Right lower quadrant abdominal tenderness R10.814 Left lower quadrant abdominal tenderness R10.815 Periumbilic abdominal tenderness R10.816 Epigastric abdominal tenderness R10.819 Abdominal tenderness, unspecified site R10.822 Left upper quadrant rebound abdominal tenderness R10.823 Right lower quadrant rebound abdominal tenderness R10.824 Left lower quadrant rebound abdominal tenderness R10.825 Periumbilic rebound abdominal tenderness R10.826 Epigastric rebound abdominal tenderness R10.83 Colic R10.84 Generalized abdominal pain R10.9 Unspecified abdominal pain R39.82 Chronic bladder pain
Abnormal bleeding	R68.9 Coagulation defect, unspecified
Abnormal pap smear of cervix (ASC-H)	R87.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of cervix (ASC-H)
Abnormal pap smear of cervix (ASC-US)	R87.610 Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)
Abnormal pap smear of cervix (LGSIL)	R87.612 Low grade squamous intraepithelial lesion on cytologic smear of cervix (LGSIL)
Abnormal pap smear of vagina (ASC-US)	R87.620 Atypical squamous cells of undetermined significance on cytologic smear of vagina (ASC-US)
Abnormal pap smear of vagina (LGSIL)	R87.622 Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
Abnormal pap smear or vagina (HGSIL)	R87.623 High grade squamous intraepithelial lesion on cytologic smear of vagina (HGSIL)
Abnormal uterine bleeding (disorder)	N93.8 Other specified abnormal uterine and vaginal bleeding N93.9 Abnormal uterine and vaginal bleeding, unspecified
Abscess of vulva (disorder)	N76.4 Abscess of vulva
Acquired hypothyroidism (disorder)	E03.8 Other specified hypothyroidism E03.9 Hypothyroidism, unspecified
Abnormal bleeding	R68.9 Coagulation defect, unspecified
Abnormal pap smear of cervix (ASC-H)	R87.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of cervix (ASC-H)
Abnormal pap smear of cervix (ASC-US)	R87.610 Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)
Abnormal pap smear of cervix (LGSIL)	R87.612 Low grade squamous intraepithelial lesion on cytologic smear of cervix (LGSIL)
Abnormal pap smear of vagina (ASC-US)	R87.620 Atypical squamous cells of undetermined significance on cytologic smear of vagina (ASC-US)
Abnormal pap smear of vagina (LGSIL)	R87.622 Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
Abnormal pap smear or vagina (HGSIL)	R87.623 High grade squamous intraepithelial lesion on cytologic smear of vagina (HGSIL)
Abnormal uterine bleeding (disorder)	N93.8 Other specified abnormal uterine and vaginal bleeding N93.9 Abnormal uterine and vaginal bleeding, unspecified
Abscess of vulva (disorder)	N76.4 Abscess of vulva
Acquired hypothyroidism (disorder)	E03.8 Other specified hypothyroidism E03.9 Hypothyroidism, unspecified
Acute herpes simplex pharyngitis (disorder)	B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
Acute renal failure syndrome (disorder)	N17.0 Acute kidney failure with tubular necrosis N17.1 Acute kidney failure with acute cortical necrosis N17.2 Acute kidney failure with medullary necrosis N17.8 Other acute kidney failure N17.9 Acute kidney failure, unspecified N18.9 Chronic kidney disease, unspecified
Adenocarcinoma in situ of cervix (disorder)	D06.0 Carcinoma in situ of endocervix D06.1 Carcinoma in situ of exocervix D06.7 Carcinoma in situ of other parts of cervix D06.9 Carcinoma in situ of cervix, unspecified
Abnormal bleeding	R68.9 Coagulation defect, unspecified
Abnormal pap smear of cervix (ASC-H)	R87.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of cervix (ASC-H)
Abnormal pap smear of cervix (ASC-US)	R87.610 Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)
Adverse reaction caused by drug (disorder)	No longer available: J98.4 Other disorders of lung P28.89 Other specified respiratory conditions of newborn
Allergic contact gingivostomatitis	B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
Amenorrhea	N91.0 Primary amenorrhea N91.1 Secondary amenorrhea N91.2 Amenorrhea, unspecified
Anemia in neoplastic disease (disorder)	D63.0 Anemia in neoplastic disease
Anemia of chronic renal failure (disorder)	D63.1 Anemia in chronic kidney disease
Anxiety (finding)	F06.4 Anxiety disorder due to known physiological condition F41.0 Panic disorder [episodic paroxysmal anxiety] F41.1 Generalized anxiety disorder F41.3 Other mixed anxiety disorders F41.8 Other specified anxiety disorders F41.9 Anxiety disorder, unspecified
Ascites (disorder)	R18.0 Malignant ascites R18.8 Other ascites
Atypical endometrial hyperplasia (disorder)	N85.00 Endometrial hyperplasia, unspecified N85.01 Benign endometrial hyperplasia N85.02 Endometrial intraepithelial neoplasia [EIN]
Atypical squamous cells on vaginal Papanicolaou smear cannot exclude high grade squamous intraepithelial lesion (finding)	R87.621 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H)
Bartholin abscess	N75.0 Cyst of Bartholin’s gland N75.1 Abscess of Bartholin’s gland N75.8 Other diseases of Bartholin’s gland N75.9 Disease of Bartholin’s gland, unspecified
Bartholin Cyst	N75.0 Cyst of Bartholin’s gland N75.1 Abscess of Bartholin’s gland N75.8 Other diseases of Bartholin’s gland N75.9 Disease of Bartholin’s gland, unspecified
Basal cell carcinoma of skin (disorder)	C44.01 Basal cell carcinoma of skin of lip C44.111 Basal cell carcinoma of skin of unspecified eyelid, including canthus C44.1121 Basal cell carcinoma of skin of right upper eyelid, including canthus C44.1122 Basal cell carcinoma of skin of right lower eyelid, including canthus C44.1191 Basal cell carcinoma of skin of left upper eyelid, including canthus C44.1192 Basal cell carcinoma of skin of left lower eyelid, including canthus C44.211 Basal cell carcinoma of skin of unspecified ear and external auricular canal C44.212 Basal cell carcinoma of skin of right ear and external auricular canal C44.219 Basal cell carcinoma of skin of left ear and external auricular canal C44.310 Basal cell carcinoma of skin of unspecified parts of face C44.311 Basal cell carcinoma of skin of nose C44.319 Basal cell carcinoma of skin of other parts of face C44.41 Basal cell carcinoma of skin of scalp and neck C44.510 Basal cell carcinoma of anal skin C44.511 Basal cell carcinoma of skin of breast C44.519 Basal cell carcinoma of skin of other part of trunk C44.611 Basal cell carcinoma of skin of unspecified upper limb, including shoulder C44.612 Basal cell carcinoma of skin of right upper limb, including shoulder C44.619 Basal cell carcinoma of skin of left upper limb, including shoulder C44.711 Basal cell carcinoma of skin of unspecified lower limb, including hip C44.712 Basal cell carcinoma of skin of right lower limb, including hip C44.719 Basal cell carcinoma of skin of left lower limb, including hip C44.91 Basal cell carcinoma of skin, unspecified
Benign endometrial hyperplasia (disorder)	N85.01 Benign endometrial hyperplasia
Benign genital neoplasm (disorder)	D28.9 Benign neoplasm of female genital organ, unspecified D29.9 Benign neoplasm of male genital organ, unspecified
Benign neoplasm of body of uterus (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of endometrium (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of female genital organ	D28.9 Benign neoplasm of female genital organ, unspecified
Benign neoplasm of fundus uteri (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of isthmus of uterus (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of myometrium (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of placenta (disorder)	D26.7 Other benign neoplasm of other parts of uterus
Benign neoplasm of uterus (disorder)	D26.9 Other benign neoplasm of uterus, unspecified
Benign neoplasm of vulva	D28.0 Benign neoplasm of vulva
Blood coagulation disorder (disorder)	R68.9 Coagulation defect, unspecified
Breakthrough cancer pain (finding)	G89.3 Neoplasm related pain (acute) (chronic)
Candidiasis of vagina (disorder)	B37.3 Candidiasis of vulva and vagina
Candidiasis of vulva	B37.3 Candidiasis of vulva and vagina
Carcinoma in situ of uterus (disorder)	D07.0 Carcinoma in situ of endometrium
Carcinoma in situ of vagina (disorder)	D07.2 Carcinoma in situ of vagina
Carcinoma in situ of vulva (disorder)	D07.1 Carcinoma in situ of vulva
Carcinomatosis (disorder)	C80.0 Disseminated malignant neoplasm, unspecified
Cervical intraepithelial neoplasia grade 2 (disorder)	N87.1 Moderate cervical dysplasia
Cervical stenosis	N88.2 Stricture and stenosis of cervix uteri
Chorioangioma (disorder)	D26.7 Other benign neoplasm of other parts of uterus
Complex atypical endometrial hyperplasia (disorder)	N85.00 Endometrial hyperplasia, unspecified N85.01 Benign endometrial hyperplasia N85.02 Endometrial intraepithelial neoplasia [EIN]
Condyloma acuminata of vulva (disorder)	A63.0 Anogenital (venereal) warts
Cyst of vagina (disorder)	N89.8 Other specified noninflammatory disorders of vagina
Disorder of female reproductive system	N94.9 Unspecified condition associated with female genital organs and menstrual cycle
Dysmenorrhea (disorder)	N94.4 Primary dysmenorrhea N94.5 Secondary dysmenorrhea N94.6 Dysmenorrhea, unspecified
Endometrial hyperplasia	N85.00 Endometrial hyperplasia, unspecified N85.01 Benign endometrial hyperplasia N85.02 Endometrial intraepithelial neoplasia [EIN]
Endometrial polyp	N84.0 Polyp of corpus uteri
Endometriosis	N80.9 Endometriosis, unspecified
Endometriosis of appendix (disorder)	N80.5 Endometriosis of intestine
Endometriosis of colon (disorder)	N80.5 Endometriosis of intestine
Benign endometrial hyperplasia (disorder)	N85.01 Benign endometrial hyperplasia
Benign genital neoplasm (disorder)	D28.9 Benign neoplasm of female genital organ, unspecified D29.9 Benign neoplasm of male genital organ, unspecified
Benign neoplasm of body of uterus (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of endometrium (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of female genital organ	D28.9 Benign neoplasm of female genital organ, unspecified
Benign neoplasm of fundus uteri (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of isthmus of uterus (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of myometrium (disorder)	D26.1 Other benign neoplasm of corpus uteri
Benign neoplasm of placenta (disorder)	D26.7 Other benign neoplasm of other parts of uterus
Benign neoplasm of uterus (disorder)	D26.9 Other benign neoplasm of uterus, unspecified
Benign neoplasm of vulva	D28.0 Benign neoplasm of vulva
Blood coagulation disorder (disorder)	R68.9 Coagulation defect, unspecified
Breakthrough cancer pain (finding)	G89.3 Neoplasm related pain (acute) (chronic)
Candidiasis of vagina (disorder)	B37.3 Candidiasis of vulva and vagina
Candidiasis of vulva	B37.3 Candidiasis of vulva and vagina
Carcinoma in situ of uterus (disorder)	D07.0 Carcinoma in situ of endometrium
Carcinoma in situ of vagina (disorder)	D07.2 Carcinoma in situ of vagina
Endometriosis of pelvic peritoneum (disorder)	N80.3 Endometriosis of pelvic peritoneum
Endometriosis of vagina (disorder)	N80.4 Endometriosis of rectovaginal septum and vagina
Endometrium thickened (finding)	R93.89 Abnormal findings on diagnostic imaging of other specified body structures
Exposure to diethylstilbestrol in utero (event)	P04.18 Newborn affected by other maternal medication
Female urethrocele (disorder)	N81.0 Urethrocele
Female urethrocele without uterine prolapse	N81.0 Urethrocele
Fibroids	D25.0 Submucous leiomyoma of uterus D25.1 Intramural leiomyoma of uterus D25.2 Subserosal leiomyoma of uterus D25.9 Leiomyoma of uterus, unspecified
Foreign body in vagina	S30.854A Superficial foreign body of vagina and vulva, initial encounter S30.854D Superficial foreign body of vagina and vulva, subsequent encounter S30.854S Superficial foreign body of vagina and vulva, sequela T19.2XXA Foreign body in vulva and vagina, initial encounter T19.2XXD Foreign body in vulva and vagina, subsequent encounter T19.2XXS Foreign body in vulva and vagina, sequela
Foreign body in vulva	S30.854A Superficial foreign body of vagina and vulva, initial encounter S30.854D Superficial foreign body of vagina and vulva, subsequent encounter S30.854S Superficial foreign body of vagina and vulva, sequela T19.2XXA Foreign body in vulva and vagina, initial encounter T19.2XXD Foreign body in vulva and vagina, subsequent encounter T19.2XXS Foreign body in vulva and vagina, sequela
Genetic susceptibility to endometrium cancer (finding)	Z15.04 Genetic susceptibility to malignant neoplasm of endometrium
Gestational trophoblastic disease (disorder)	D39.0 Neoplasm of uncertain behavior of uterus
Hematometra	N85.7 Hematometra
Herpes barbae (disorder)	B00.1 Herpesviral vesicular dermatitis
Herpes labialis (disorder)	B00.1 Herpesviral vesicular dermatitis
Herpes simplex (disorder)	B00.9 Herpesviral infection, unspecified
History of dysplasia of cervix (situation)	Z87.410 Personal history of cervical dysplasia
History of endometrial hyperplasia	Z87.42 Personal history of other diseases of the female genital tract
Hydatid cyst of Morgagni – female (disorder)	Q50.4 Embryonic cyst of fallopian tube Q50.5 Embryonic cyst of broad ligament Q50.6 Other congenital malformations of fallopian tube and broad ligament
Hydrosalpinx (disorder)	N70.01 Acute salpingitis N70.02 Acute oophoritis N70.03 Acute salpingitis and oophoritis N70.11 Chronic salpingitis N70.12 Chronic oophoritis N70.13 Chronic salpingitis and oophoritis N70.91 Salpingitis, unspecified N70.92 Oophoritis, unspecified N70.93 Salpingitis and oophoritis, unspecified
Imperforate hymen	Q52.3 Imperforate hymen
Incompetence of pubocervical tissue	N81.82 Incompetence or weakening of pubocervical tissue
Incompetence of rectovaginal tissue (finding)	N81.83 Incompetence or weakening of rectovaginal tissue
Infection caused by Molluscum contagiosum (disorder)	B08.1 Molluscum contagiosum
Insertion of intrauterine contraceptive device	Z30.430 Encounter for insertion of intrauterine contraceptive device
Invasive hydatidiform mole (disorder)	D39.2 Neoplasm of uncertain behavior of placenta
Leukoplakia of vagina	N90.4 Leukoplakia of vulva
Lichen sclerosus of vulva	N90.4 Leukoplakia of vulva
Malignant ascites (disorder)	R18.0 Malignant ascites
Menorrhagia	N92.0 Excessive and frequent menstruation with regular cycle N92.1 Excessive and frequent menstruation with irregular cycle N92.2 Excessive menstruation at puberty N92.3 Ovulation bleeding N92.4 Excessive bleeding in the premenopausal period N92.5 Other specified irregular menstruation N92.6 Irregular menstruation, unspecified
Endometriosis of pelvic peritoneum (disorder)	N80.3 Endometriosis of pelvic peritoneum
Endometriosis of vagina (disorder)	N80.4 Endometriosis of rectovaginal septum and vagina
Endometrium thickened (finding)	R93.89 Abnormal findings on diagnostic imaging of other specified body structures
Exposure to diethylstilbestrol in utero (event)	P04.18 Newborn affected by other maternal medication
Menometrorrhagia	N92.1 Excessive and frequent menstruation with irregular cycle
Mittelschmerz	N94.0 Mittelschmerz
Mucinous cystadenoma of left ovary (disorder)	D27.1 Benign neoplasm of left ovary
Mucinous cystadenoma of right ovary (disorder)	D27.0 Benign neoplasm of right ovary
Neoplasm of uterus (disorder)	C55 Malignant neoplasm of uterus, part unspecified D07.0 Carcinoma in situ of endometrium
Pain in female pelvis (finding)	R10.2 Pelvic and perineal pain
Pelvic mass	R19.00 Intra-abdominal and pelvic swelling, mass and lump, unspecified site R19.03 Right lower quadrant abdominal swelling, mass and lump R19.04 Left lower quadrant abdominal swelling, mass and lump
	R19.07 Generalized intra-abdominal and pelvic swelling, mass and lump R19.09 Other intra-abdominal and pelvic swelling, mass and lump
Postcoital bleeding (finding)	N93.0 Postcoital and contact bleeding
PPE	L27.1 Localized skin eruption due to drugs and medicaments taken internally
Primary amenorrhea	N91.0 Primary amenorrhea
Primary dysmenorrhea	N94.4 Primary dysmenorrhea
Primary malignant neoplasm of clitoris (disorder)	C51.2 Malignant neoplasm of clitoris
Primary malignant neoplasm of labia majora (disorder)	C51.0 Malignant neoplasm of labium majus
Primary malignant neoplasm of labia minora	C51.1 Malignant neoplasm of labium minus
Primary malignant neoplasm of vagina (disorder)	C52 Malignant neoplasm of vagina
Primary oligomenorrhea	N91.3 Primary oligomenorrhea
Prolapse, Uterovaginal (post TAH)	N99.3 Prolapse of vaginal vault after hysterectomy
Removal of intrauterine device (procedure)	Z30.432 Encounter for removal of intrauterine contraceptive device
Screening for cancer	Z12.9 Encounter for screening for malignant neoplasm, site unspecified
Secondary Amenorrhea	N91.1 Secondary amenorrhea
Secondary dysmenorrhea (disorder)	N94.5 Secondary dysmenorrhea
Secondary oligomenorrhea	N91.4 Secondary oligomenorrhea
Secondary physiologic amenorrhea (finding)	N91.1 Secondary amenorrhea
Simple atypical endometrial hyperplasia (disorder)	N85.00 Endometrial hyperplasia, unspecified N85.01 Benign endometrial hyperplasia N85.02 Endometrial intraepithelial neoplasia [EIN]
Submucous leiomyoma of uterus (disorder)	D25.0 Submucous leiomyoma of uterus
Subserous leiomyoma of uterus (disorder)	D25.2 Subserosal leiomyoma of uterus
Submucous uterine fibroid	D25.0 Submucous leiomyoma of uterus
Subserous uterine fibroid	D25.2 Subserosal leiomyoma of uterus
Torsion of ovary (disorder)	N83.511 Torsion of right ovary and ovarian pedicle N83.512 Torsion of left ovary and ovarian pedicle N83.519 Torsion of ovary and ovarian pedicle, unspecified side N83.521 Torsion of right fallopian tube N83.522 Torsion of left fallopian tube N83.529 Torsion of fallopian tube, unspecified side N83.53 Torsion of ovary, ovarian pedicle and fallopian tube
Ulceration of vulva (disorder)	N76.6 Ulceration of vulva
Ulcerative mucositis of vagina (disorder)	N76.81 Mucositis (ulcerative) of vagina and vulva
Ulcerative mucositis of vulva (disorder)	N76.81 Mucositis (ulcerative) of vagina and vulva
Uterine leiomyoma (disorder)	D25.0 Submucous leiomyoma of uterus D25.1 Intramural leiomyoma of uterus D25.2 Subserosal leiomyoma of uterus D25.9 Leiomyoma of uterus, unspecified
Uterovaginal prolapse (disorder)	N81.2 Incomplete uterovaginal prolapse N81.3 Complete uterovaginal prolapse N81.4 Uterovaginal prolapse, unspecified
Uterovaginal prolapse, incomplete (disorder)	N81.2 Incomplete uterovaginal prolapse
Vaginal cyst	N89.8 Other specified noninflammatory disorders of vagina
Vaginal discharge (finding)	N89.8 Other specified noninflammatory disorders of vagina
Vaginal intraepithelial neoplasia grade 2 (disorder)	N89.1 Moderate vaginal dysplasia
Vaginal lesion	N89.8 Other specified noninflammatory disorders of vagina
VAIN III – Vaginal intraepithelial neoplasia grade III	D07.2 Carcinoma in situ of vagina
VIN – Vulval intraepithelial neoplasia grade 1	N90.0 Mild vulvar dysplasia
Vulval intraepithelial neoplasia grade 2 (disorder)	N90.1 Moderate vulvar dysplasia
Vulvar condyloma	A63.0 Anogenital (venereal) warts
Vulvar cyst	N90.7 Vulvar cyst
Vulvar ulceration	N76.6 Ulceration of vulva
Vulvar vestibulitis (disorder)	N94.810 Vulvar vestibulitis
Vulvitis (disorder)	N76.0 Acute vaginitis N76.1 Subacute and chronic vaginitis N76.2 Acute vulvitis N76.3 Subacute and chronic vulvitis
Vulvovaginitis	N76.0 Acute vaginitis
Uterovaginal prolapse, incomplete (disorder)	N81.2 Incomplete uterovaginal prolapse
Vaginal cyst	N89.8 Other specified noninflammatory disorders of vagina
Vaginal discharge (finding)	N89.8 Other specified noninflammatory disorders of vagina
Vaginal intraepithelial neoplasia grade 2 (disorder)	N89.1 Moderate vaginal dysplasia
Vaginal lesion	N89.8 Other specified noninflammatory disorders of vagina
VAIN III – Vaginal intraepithelial neoplasia grade III	D07.2 Carcinoma in situ of vagina
VIN – Vulval intraepithelial neoplasia grade 1	N90.0 Mild vulvar dysplasia
Vulval intraepithelial neoplasia grade 2 (disorder)	N90.1 Moderate vulvar dysplasia
Vulvar condyloma	A63.0 Anogenital (venereal) warts
Vulvar cyst	N90.7 Vulvar cyst
Vulvar ulceration	N76.6 Ulceration of vulva
Vulvar vestibulitis (disorder)	N94.810 Vulvar vestibulitis
Vulvitis (disorder)	N76.0 Acute vaginitis N76.1 Subacute and chronic vaginitis N76.2 Acute vulvitis N76.3 Subacute and chronic vulvitis
Vulvovaginitis	N76.0 Acute vaginitis
Uterovaginal prolapse, incomplete (disorder)	N81.2 Incomplete uterovaginal prolapse
Vaginal cyst	N89.8 Other specified noninflammatory disorders of vagina

Lab Analytes, Panels and Other Services

Additions

Adenovirus DNA, QN real time PCR, Log copies/mL
AV-R7, genomic panel
BK virus DNA, QN real time PCR, blood, Log copies/mL
BK virus DNA, QN real time PCR, urine, Log copies/mL
BRAF, tissue panel
Breast cancer index panel
Bullous pemphigoid BP180 ab panel
Bullous pemphigoid BP230 ab panel
Cancer type ID panel
Coag factor II activity, % normal
Cobas SARS-CoV-2 & influenza A/B multiplex, RT PCR panel
Coccidioides Ab, IgG, EIA, EIA units
Coccidioides Ab, IgM, EIA, EIA units
Cryptococcus ab, quant panel
Culture, anaerobic bacteria w/gram stain
DecisionDx SCC panel
DsDNA ab, high avidity, IU/mL
DsDNA Crithidia luciliae IFA, qual
EGFR, tissue panel
EGFR,ctDNA panel
EZH2 panel
FIB-4 index
FIB-4 interpretation
FISH, follicular lymphoma panel
FISH, Follicular lymphoma, IGH/BCL2, t(14;18)
Gastrointestinal profile, stool, PCR panel
Genomic testing COOP panel
Guardant360 CDX panel
Guideline based hereditary cancer panel
HER2, tissue panel
Homocysteine, mEq/L
Influenza A
Influenza B
Invitae BRCA1 and BRCA2 STAT panel results
Invitae BRCA1 and BRCA2 STAT panel
Invitae breast and gyn cancers panel + preliminary-evidence genes for breast and gyn cancer results
Invitae breast and gyn cancers panel + preliminary-evidence genes for breast and gyn cancer
Invitae breast cancer panel + preliminary-evidence genes for breast cancer results
Invitae breast cancer panel + preliminary-evidence genes for breast cancer
Invitae breast cancer STAT panel + ATM and CHEK2 results
Invitae breast cancer STAT panel + ATM and CHEK2
Invitae colorectal cancer panel + preliminary- evidence genes for colorectal cancer results
Invitae colorectal cancer panel + preliminary- evidence genes for colorectal cancer
Invitae hereditary myelodysplastic syndrome/leukemia panel + preliminary-evidence genes for myelodysplastic syndrome results
Invitae hereditary myelodysplastic syndrome/leukemia panel + preliminary-evidence genes for myelodysplastic syndrome
Invitae melanoma panel + preliminary-evidence genes for melanoma results
Invitae melanoma panel + preliminary-evidence genes for melanoma
Invitae MRD panel
Invitae multi-cancer + RNA panel results
Invitae multi-cancer + RNA panel
Invitae multi-cancer panel result
Invitae nervous system/brain cancer panel + hereditary paraganglioma- pheochromocytoma genes and preliminary-evidence genes for nervous system/brain cancer results
Invitae nervous system/brain cancer panel + hereditary paraganglioma- pheochromocytoma genes and preliminary-evidence genes for nervous system/brain cancer
Invitae pancreatic cancer panel + chronic pancreatitis genes and preliminary- evidence genes for pancreatic cancer results
Invitae pancreatic cancer panel + chronic pancreatitis genes and preliminary- evidence genes for pancreatic cancer
Invitae prostate cancer HRR panel results
Invitae Prostate cancer HRR panel
Invitae prostate cancer panel + preliminary- evidence genes for prostate cancer results
Invitae prostate cancer panel + preliminary- evidence genes for prostate cancer
Invitae renal/urinary tract cancers panel + preliminary-evidence genes for renal/urinary tract cancers results
Invitae renal/urinary tract cancers panel + preliminary-evidence genes for renal/urinary tract cancers
JAK2 V617F mutation % alleles, whole blood
JAK2 V617F mutation analysis whole blood panel
JAK2 V617F mutation interpretation, whole blood
KIT D816 mutation interpretation
KRAS, ctDNA panel
MyRisk BRCA panel
MyRisk CDX panel
MyRisk colaris panel
NRAS mutation analysis paraffin block number
NRAS mutation analysis specimen source
NTRK fusion panel
OncoMap panel
Progesteron receptor (PR) panel
SARS-CoV-2
Signatera clonality panel
Signatera tracker panel
Tartrate resistant acid phosphatase (TRAP), IU/L
Tempus xG panel
Testosterone, free, LC/MS/MS panel
Testosterone, free, pg/mL
Thyroglobulin ab (TGAB) comment

Nursing Procedures

Additions

Urea nitrogen 24 hr urine panel
Urea nitrogen, 24 hr urine, mg/24hr
Urea nitrogen, timed urine
Urea nitrogen, urine
Urea nitrogen, urine, mg/g CRT
VeriStrat panel
von Hippel-Lindau disease (VHL) additional information
von Hippel-Lindau disease (VHL) method and limitations
von Hippel-Lindau disease (VHL) panel
von Hippel-Lindau disease (VHL) resource
von Hippel-Lindau disease (VHL) reviewer
von Hippel-Lindau disease (VHL) test

A procedure for BMP was created to align term mapping of 80048.

Medications

Additions

AGEN1181 invest IV
Alpelisib Oral (VIJOICE)
ALX148 invest IV
AMG 193 invest Oral
ART0380 invest Oral
BI 765049 invest IV
BMS-986406 invest IV
BP1001-A invest IV
Coagulation Factor X IV
CS5001 invest IV
DAY101 invest Oral
ENV-1010 invest (Taladegib invest Oral)
HY-0102 invest IV
IO-202 invest IV
LM-108 invest IV
MDNA11 invest IV
Milademetan invest Oral
Modakafusp alfa invest (TAK-573 invest IV)
Morphine Topical Gel 1 %
NUV-868 invest Oral
RMC-6236 invest Oral
RTX-224 invest IV
Taladegib invest Oral
Taletrectinib invest Oral
UCT-01-097 invest Oral
UCT-03-008 invest Oral
XmAb24306 invest IV
XTX101 invest IV

Updates

Medication	Update
ABI-009 invest IV	New Dose(s) available: 35 mg/m2 45 mg/m2 56 mg/m2 75 mg/m2 100 mg/m2
Enfortumab Vedotin-ejfv IV	New Instructions available: Dilute in D5W, NS or LR to achieve a final concentration of 0.3 to 4 mg/mL. Mix diluted solution by gentle inversion. Do not shake, do not expose to direct sunlight. Do not administer IV push or bolus. Do not mix or administer with other drugs. See prescribing information for detailed instructions on dose reductions and associated max dose limits.
Morphine Topical Gel 0.1 %	New Unit available: Grams
NC318 invest IV	New Quick Sig available: 800 mg intravenously As Directed; administer over 30 minutes; every week for 8 cycles, then every 2 weeks thereafter
Paclitaxel IV	New Instructions for “once” or “over 3 hours” Dilute in 250-500 mL of NS. Rate per cited reference. Administer using Non-DEHP-containing equipment and through an in-line 0.22 micron filter. Paclitaxel is an irritant.
Paclitaxel IV	New Instructions for “over 24 hours” or “for 24 hours” Dilute in NS (CADD). Rate per cited reference; via ambulatory pump. Refer to drug stability guidelines for chemotherapy agent. Paclitaxel is an irritant.
SV-BR-1-GM invest Intradermal	New Forms available: SV-BR-1-GM invest 1 (+/-0.2) x 10e6 cells solution SV-BR-1-GM invest 20 (+/-5) x 10e6 cells solution

Regimens

This section does not include clinical trial regimens.

Additions

Regimen Name	Diagnosis
Mitapivat Q28D	Anemia, Hemolytic
Bevacizumab (7.5 mg/kg) BIOSIMILAR Q21D (Colon, Rectal) (Addition to Chemotherapy)	Colon Cancer; Rectal Cancer
Docetaxel + Darolutamide + ADT Q21D (Docetaxel only)	Prostate Cancer
Docetaxel + Darolutamide + ADT Q28D (Darolutamide + Leuprolide only)	Prostate Cancer
Docetaxel + Darolutamide + ADT Q28D (Darolutamide + Goserelin only)	Prostate Cancer
Pemetrexed + Bevacizumab (15 mg/kg) BIOSIMILAR Q21D (Maintenance)	Lung Cancer, Non-small Cell (NSCLC)
Pemetrexed + Carboplatin + Bevacizumab BIOSIMILAR Q21D	Lung Cancer, Non-small Cell (NSCLC)
Selinexor D1,8,15 + Carfilzomib D1,8,15 + Dexamethasone Q28D	Multiple Myeloma (MM)
Selinexor D1,8,15,22 + Pomalidomide D1-21 + Dexamethasone Q28D	Multiple Myeloma (MM)

Updates

Regimens for the following diagnoses have been updated based on the Collaborative Care Committee voting. Changes include but are not limited to reference update, drug infusion instruction updates, renaming of regimens, premedication template updates and number of cycles.

All Problems
Bile Duct Cancer (Parent)
Breast Cancer
Gestational Trophoblastic Tumor
Leukemia, Acute Lymphocytic (ALL)
Leukemia, Acute Myeloid (AML)
Leukemia, Chronic Lymphocytic (CLL)
Leukemia, Chronic Myeloid (CML)
Lung Cancer, Non-small Cell (NSCLC)
Lung Cancer, Small Cell (SCLC)
Lymphoma, Hodgkin (HL)
Lymphoma, Non-Hodgkin (NHL) (Parent)
Merkel Cell Carcinoma
Fallopian Tube Cancer
Gallbladder Cancer
Gastric Cancer
Mycosis Fungoides/Sezary Syndrome
Neuroendocrine Tumor, Carcinoid (Parent)
Ovarian and Primary Peritoneal Cancer
Primary Cutaneous Lymphoma
Prostate Cancer
Rectal Cancer
Renal Cell Carcinoma (RCC)
Sarcoma, Bone (Parent)
Sarcoma, Soft Tissue (Parent)
Testicular Cancer (Parent)
Thymoma, Malignant
Uterine Cancer (Parent)
Waldenstrom’s Macroglobulinemia

Removals

Atezolizumab D1,15 + Abraxane D1,8,15 Q28D
BEACOPP (Escalated) Q21D fb ABVD Q28D (Part 1 of 2: BEACOPP Escalated Only)
BEACOPP (Escalated) Q21D fb ABVD Q28D (Part 2 of 2: ABVD Only)
Liposomal Vincristine Q7D
Pemetrexed + Bevacizumab (7.5 mg/kg) Q21D
Pneumococcal Vaccine (Revaccination)
Pneumococcal Vaccine D1,56 Q56D
Umbralisib Q30D

Renames

Previous Name	New Name
Immunotherapy-related Toxicity Supportive Care Regimen	Immunotherapy-Related Toxicity Supportive Care
Rituximab IV BIOSIMILAR + DHAP (Carboplatin) Q21D (MCL)	Rituximab IV BIOSIMILAR + DHAP (Carboplatin) Q21D
Rituximab IV BIOSIMILAR + DHAP (Oxaliplatin) Q21D (MCL)	Rituximab IV BIOSIMILAR + DHAP (Oxaliplatin) Q21D
Rituximab IV BIOSIMILAR D1,8,15 + DHAP (Cisplatin) Q21D	Rituximab IV BIOSIMILAR + DHAP (Cisplatin) Q21D

Research

Additions

To support Data Migration, applicable clinical trial regimens for US Oncology Research have been migrated and modified for customers migrating from iKnowMed Generation 1 to iKnowMed Generation 2.

Updates

	Updated Reference Information	Updated Drug Service Order Information	Updated Regimen Instructions	Other Changes
USOR 18020	X	X	X
USOR 18126				No longer available: USOR 18126 Part D SEA-BCMA Intensive Dosing + Pomalidomide D1-21 + Dexamethasone (Weekly) Q28D USOR 18126 Part E SEA-BCMA Intensive Dosing + Nirogacestat PO BID + Dexamethasone IV (Weekly) Q28D
USOR 19113	X	X	X
USOR 19151	X	X	X
USOR 19221	X		X	No longer available: USOR 19221 Chemotherapy Phase Durvalumab or Placebo + Paclitaxel + Carboplatin Q21D
USOR 20150	X	X
USOR 20169	X	X	X
USOR 20235		X
USOR 20285	X		X
USOR 20305	X		X	Now available: USOR 20305 BAY 2416964 (PO; TID) + Pembrolizumab Q21D
USOR 20331	X
USOR 21235	X			No longer available: USOR 21235 NIS793 or Placebo D1 + Nab-Paclitaxel D1,8,15 + Gemcitabine D1,8,15 Q28D
USOR 21242	X
USOR 21309	X	X	X
USOR 21320	X	X	X
USOR 21412	X		X
USOR 21449	X

Billing & HCPCS Codes

Bortezomib Billing Guidance

The billing for this medication can be a bit tricky due to two different HCPCS billing codes:

J9041 for Velcade or its equivalent generic (Bortezomib)
J9044 for Bortezomib, Not Otherwise Specified

The best course of action to ensure the charge capture renders the correct code is to document the NDC that corresponds with the medication administered.

If the NDC is not documented, we suggest reviewing the charge capture to confirm the billing code. If you find the billing code is incorrect, billing considerations can be used.

Updates

Medication	HCPCS Code(s)
COVID-19 Vaccine, Antigen (Sanofi) (PF) IM (Booster) (Unapproved)	91310 per 0.5 mL
Dexamethasone sodium Phos (PF) IV	J1100 per 1mg